Sent from my iPad Begin forwarded message:

From: Genetic Engineering & Biotechnology News <gen@genmail.co> Date: April 2, 2025 at 11:01:58 AM GMT-3 To: mxh5000@gmail.com Subject: Autism Symptoms in Mice Linked To Nerve Proteins Falling Out of Equilibrium Reply-To: gen@genmail.co

View in browser

TOP STORIES Wednesday, April 2, 2025

Autism Symptoms in Mice Linked To Nerve Proteins Falling Out of Equilibrium

Scientists found that autism symptoms in mice arise when a pair of nerve proteins falls out of equilibrium. The collective findings demonstrated that MDGA2 deficiency results in aberrant BDNF/TrkB activation, ultimately leading to ASD-like phenotypes. + MORE

FDA, NIH, CDC Stagger as HHS Axe Falls, Eliminating 10,000 Jobs

The 10,000 jobs being eliminated include 3,500 positions at the FDA, 2,400 at the U.S. Centers for Disease Control and Prevention (CDC), and 1,200 at the NIH. + MORE

IDT Lengthens DNA Offerings with Elegen Partnership

IDT and Elegen partner to launch an early access program offering long, clonal gene synthesis and high-complexity genes up to 15 kb. Customers can order through IDT and the DNA will be manufactured and shipped from Elegen. + MORE

ALS Consortium Launches Website to Advance ALS Research

ASSESS ALL ALS is for people living with the disease and healthy people who will act as comparators. PREVENT ALL ALS is for people who may be at genetic risk for ALS. + MORE

SPONSORED Expand Your NGS Multiplexing Capabilities

Dramatically lower your sequencing costs without changing your library prep protocol with the set of 1,536 NEXTFLEX™ UDI adapters. Alternatively, the NEXTFLEX UDI-UMI adapters enable rare variant analysis in PCR-free libraries. Learn more. For research use only. Not for use in diagnostic procedures. + MORE Input Determines Output: Building a Protein Expression Platform

To find out more about ongoing advances in developing cell lines for protein expression, GEN talked with three experts from China, Denmark, and the U.S. + MORE

Practicing Viral Vigilance Over Cell Culture-Based Processes

Researchers envision ongoing advances in monitoring EBV and OvHV-2 viruses. For example, scientists point out that “incorporating high-throughput sequencing and single-cell analysis into EBV and OvHV-2 detection processes could reveal viral diversity within cell cultures.” + MORE

UPCOMING WEBINARS NGS Workflows for Expedited Development & Manufacturing of Therapeutic Antibodies

In TODAY's GEN webinar, scientists from Moderna and seqWell will present several applications of a fully scalable, one-step NGS library preparation workflow that span antibody development and biomanufacturing. + MORE

An Automated, High-Throughput Approach for Stability Testing in Protein, Cell, and Gene Therapeutics

In this GEN webinar, Dr. Karessa White will explore how the Aura platforms offer rapid screening to assess biological aggregation and extrinsic particulate contamination in protein, cell and gene therapeutics, from initial product selection to the manufacturing stage. + MORE

Genetic Engineering & Biotechnology News Mary Ann Liebert, Inc., a Sage Company 140 Huguenot Street New Rochelle, NY 10801 You have received this email at mxh5000@gmail.com Unsubscribe Manage Preferences