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| | | | | | | Physical Sciences | | | Applied Physical Sciences | |
| Biophysics and Computational Biology | |
| | Earth, Atmospheric, and Planetary Sciences | |
| Engineering | A closed-loop modular multiorgan-on-chips platform for self-sustaining and tightly controlled oxygenation | Nan Jiang, Guoliang Ying, Yixia Yin, Jie Guo, Jorge Lozada, Alejandra Valdivia Padilla, Ameyalli Gómez, Bruna Alice Gomes de Melo, Francisco Lugo Mestre, Merel Gansevoort, Marcello Palumbo, Noemi Calá, Carlos Ezio Garciamendez-Mijares, Ge-Ah Kim, Shuichi Takayama, Marie Denis Gerhard-Herman and Yu Shrike Zhang |
Three-chamber electrochemical reactor for selective lithium extraction from brine | Yuge Feng, Yoon Park, Shaoyun Hao, Zhiwei Fang, Tanguy Terlier, Xiao Zhang, Chang Qiu, Shoukun Zhang, Fengyang Chen, Peng Zhu, Quan Nguyen, Haotian Wang and Sibani Lisa Biswal |
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| Social Sciences | | | | Psychological and Cognitive Sciences | |
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| Biological Sciences | | Agricultural Sciences | Mismatch between lab-generated and field-evolved resistance to transgenic Bt crops in Helicoverpa zea | Andrew W. Legan, Carson W. Allan, Zoe N. Jensen, Benjamin A. Degain, Fei Yang, David L. Kerns, Kyle M. Benowitz, Jeffrey A. Fabrick, Xianchun Li, Yves Carrière, Luciano M. Matzkin and Bruce E. Tabashnik |
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| Applied Biological Sciences | A closed-loop modular multiorgan-on-chips platform for self-sustaining and tightly controlled oxygenation | Nan Jiang, Guoliang Ying, Yixia Yin, Jie Guo, Jorge Lozada, Alejandra Valdivia Padilla, Ameyalli Gómez, Bruna Alice Gomes de Melo, Francisco Lugo Mestre, Merel Gansevoort, Marcello Palumbo, Noemi Calá, Carlos Ezio Garciamendez-Mijares, Ge-Ah Kim, Shuichi Takayama, Marie Denis Gerhard-Herman and Yu Shrike Zhang |
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| Biochemistry | Discovery of highly potent and ALK2/ALK1 selective kinase inhibitors using DNA-encoded chemistry technology | Ravikumar Jimmidi, Diana Monsivais, Hai Minh Ta, Kiran L. Sharma, Kurt M. Bohren, Srinivas Chamakuri, Zian Liao, Feng Li, John M. Hakenjos, Jian-Yuan Li, Yuji Mishina, Haichun Pan, Xuan Qin, Matthew B. Robers, Banumathi Sankaran, Zhi Tan, Suni Tang, Yasmin M. Vasquez, Jennifer Wilkinson, Damian W. Young, Stephen S. Palmer, Kevin R. MacKenzie, Choel Kim and Martin M. Matzuk |
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| Biophysics and Computational Biology | |
| Cell Biology | Subchronic elevation in ambient temperature drives alterations to the sperm epigenome and accelerates early embryonic development in mice | Natalie Trigg, John E. Schjenken, Jacinta H. Martin, David A. Skerrett-Byrne, Shannon P. Smyth, Ilana R. Bernstein, Amanda L. Anderson, Simone J. Stanger, Ewan N. A. Simpson, Archana Tomar, Raffaele Teperino, Colin C. Conine, Geoffry N. De Iuliis, Shaun D. Roman, Elizabeth G. Bromfield, Matthew D. Dun, Andrew L. Eamens and Brett Nixon |
REGγ is essential to maintain bone homeostasis by degrading TRAF6, preventing osteoporosis | Yingying Du, Hui Chen, Lei Zhou, Qunfeng Guo, Shuangming Gong, Siyuan Feng, Qiujing Guan, Peilin Shi, Tongxin Lv, Yilan Guo, Cheng Yang, Peng Sun, Kun Li, Shuogui Xu and Lei Li |
Loss of XIST lncRNA unlocks stemness and cellular plasticity in ovarian cancer | Ikrame Naciri, Minzhi Liang, Ying Yang, Heather Karner, Benjamin Lin, Maria De Lourdes Andrade Ludena, Eric A. Hanse, Alfredo Lebron, Olga V. Razorenova, Dequina Nicholas, Mei Kong and Sha Sun |
PARG inhibitor sensitivity correlates with accumulation of single-stranded DNA gaps in preclinical models of ovarian cancer | Ramya Ravindranathan, Ozge Somuncu, Alexandre André B. A. da Costa, Sirisha Mukkavalli, Benjamin P. Lamarre, Huy Nguyen, Carter Grochala, Yuqing Jiao, Joyce Liu, Bose Kochupurakkal, Kalindi Parmar, Geoffrey I. Shapiro and Alan D. D’Andrea |
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| | | | | Immunology and Inflammation | Targeting PRMT7-mediated monomethylation of MAVS enhances antiviral innate immune responses and inhibits RNA virus replication | Jingjing Yang, Wenjuan Li, Zepeng Zhang, Xiaohua Gong, Yanchao Chen, Xiaoyu Peng, Guosheng Hu, Xianglong Dai, Yaohui He, Ying Huang, Shiqiang Cao, Yang Yang and Wen Liu |
Augmenting antitumor efficacy of Th17-derived Th1 cells through IFN-γ-induced type I interferon response network via IRF7 | Xiaoyi Lei, Ruipei Xiao, Zhe Chen, Jie Ren, Wenli Zhao, Wenting Tang, Kang Wen, Yihan Zhu, Xinru Li, Suidong Ouyang, Abai Xu, Yu Hu and Enguang Bi |
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| Medical Sciences | The dichotomous roles of microbial-modified bile acids 7-oxo-DCA and isoDCA in intestinal tumorigenesis | Xingchen Dong, Fei Sun, Henry Secaira-Morocho, Alisa Hui, Ke Wang, Chunmiao Cai, Shirsa Udgata, Brian Low, Songlin Wei, Xinyi Chen, Ming Qi, Cheri A. Pasch, Wei Xu, Jiaoyang Jiang, Qiyun Zhu, Tao Huan, Dustin A. Deming and Ting Fu |
Mediator kinase inhibitors suppress triple-negative breast cancer growth and extend tumor suppression by mTOR and AKT inhibitors | Xiaokai Ding, Jiaxin Liang, Amanda C. Sharko, Thomas A. Hilimire, Jing Li, Jürgen Loskutov, Zachary T. Mack, Hao Ji, Gary P. Schools, Chao Cai, Elena N. Pugacheva, Mengqian Chen, Igor B. Roninson and Eugenia V. Broude |
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| Microbiology | Structure-based design of glycoprotein subunit vaccines for mumps | Rebecca J. Loomis, Yen-Ting Lai, Sun B. Sowers, Brian Fisher, Alexandrine Derrien-Colemyn, David R. Ambrozak, Yaroslav Tsybovsky, Stephen N. Crooke, Donald R. Latner, Wing-Pui Kong, Tracy J. Ruckwardt, Stanley A. Plotkin, Peter D. Kwong, John R. Mascola, Barney S. Graham, Carole J. Hickman and Guillaume B. E. Stewart-Jones |
Modeling extrahepatic hepatitis E virus infection in induced human primary neurons | Michelle Jagst, André Gömer, Sanja Augustyniak, Mara Klöhn, Adriana Rehm, Rainer G. Ulrich, Verian Bader, Konstanze F. Winklhofer, Yannick Brüggemann, Ralf Gold, Barbara Gisevius, Daniel Todt and Eike Steinmann |
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| Neuroscience | TARGET-seq: Linking single-cell transcriptomics of human dopaminergic neurons with their target specificity | Alessandro Fiorenzano, Petter Storm, Edoardo Sozzi, Andreas Bruzelius, Sara Corsi, Janko Kajtez, Janitha Mudannayake, Jenny Nelander, Bengt Mattsson, Malin Åkerblom, Tomas Björklund, Anders Björklund and Malin Parmar |
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| Plant Biology | Targeted engineering of camelina and pennycress seeds for ultrahigh accumulation of acetyl-TAG | Linah Alkotami, Dexter J. White, Kathleen M. Schuler, Maliheh Esfahanian, Brice A. Jarvis, Andrew E. Paulson, Somnath Koley, Jinling Kang, Chaofu Lu, Doug K. Allen, Young-Jin Lee, John C. Sedbrook and Timothy P. Durrett |
Cotranscriptional splicing is required in the cold to produce COOLAIR isoforms that repress Arabidopsis FLC | Xiaogang Long, Yajun Cai, Huamei Wang, Yue Liu, Xiaoyi Huang, Hua Xuan, Wenjuan Li, Xiaoling Zhang, Hongya Zhang, Xiaofeng Fang, Hang He, Guoyong Xu, Caroline Dean and Hongchun Yang |
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| Psychological and Cognitive Sciences | |
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